HSD17B10 antibody (Internal Region)
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- Target See all HSD17B10 Antibodies
- HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HSD17B10 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificity
- ERAB Antibody detects endogenous levels of total ERAB.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ERAB, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product HSD17B10 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
- Alternative Name
- HSD17B10 (HSD17B10 Products)
- Synonyms
- hadh2 antibody, im:6899159 antibody, wu:fj61f03 antibody, zgc:101605 antibody, abad antibody, camr antibody, erab antibody, hcd2 antibody, hsd10 antibody, mhbd antibody, mrpp2 antibody, mrx17 antibody, mrx31 antibody, mrxs10 antibody, schad antibody, sdr5c1 antibody, HADH2 antibody, HSD17B10 antibody, 17b-HSD10 antibody, ABAD antibody, CAMR antibody, DUPXp11.22 antibody, ERAB antibody, HCD2 antibody, MHBD antibody, MRPP2 antibody, MRX17 antibody, MRX31 antibody, MRXS10 antibody, SCHAD antibody, SDR5C1 antibody, 17bHSD10 antibody, Ads9 antibody, Hadh2 antibody, hydroxysteroid (17-beta) dehydrogenase 10 antibody, hydroxysteroid 17-beta dehydrogenase 10 antibody, hydroxysteroid (17-beta) dehydrogenase 10 L homeolog antibody, HSD17B10 antibody, hsd17b10 antibody, hsd17b10.L antibody, Hsd17b10 antibody
- Background
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Description: Mitochondrial dehydrogenase that catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone (PubMed:9553139, PubMed:23042678, PubMed:12917011, PubMed:18996107, PubMed:25925575, PubMed:28888424). Catalyzes the third step in the beta-oxidation of fatty acids (PubMed:9553139, PubMed:12917011, PubMed:18996107, PubMed:25925575, PubMed:28888424). Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids (PubMed:12917011). Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids (PubMed:12917011). By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD) (PubMed:9338779). Essential for structural and functional integrity of mitochondria (PubMed:20077426).
Gene: HSD17B10
- Molecular Weight
- 27kDa
- Gene ID
- 3028
- UniProt
- Q99714
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