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HSPH1 antibody (C-Term)

HSPH1 Reactivity: Human, Mouse WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6262389
  • Target See all HSPH1 Antibodies
    HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))
    Binding Specificity
    • 9
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 65
    • 35
    • 34
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    Human, Mouse
    Host
    • 62
    • 7
    • 1
    Rabbit
    Clonality
    • 55
    • 15
    Polyclonal
    Conjugate
    • 43
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This HSPH1 antibody is un-conjugated
    Application
    • 50
    • 26
    • 14
    • 13
    • 12
    • 11
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    HSP105 Antibody detects endogenous levels of total HSP105.
    Predicted Reactivity
    Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human HSP105, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product HSPH1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))
    Alternative Name
    HSPH1 (HSPH1 Products)
    Synonyms
    hsp105 antibody, hsp105a antibody, hsp105b antibody, hsp110 antibody, hsph1b antibody, Hsp105 antibody, HSP105 antibody, HSP105A antibody, HSP105B antibody, NY-CO-25 antibody, 105kDa antibody, AI790491 antibody, Hsp110 antibody, hsp-E7I antibody, hsph1 antibody, hsph1a antibody, heat shock protein family H (Hsp110) member 1 antibody, heat shock protein family H (Hsp110) member 1 S homeolog antibody, heat shock protein 105 kDa antibody, heat shock 105kDa/110kDa protein 1 antibody, heat shock protein family H (Hsp110) member 1 L homeolog antibody, hsph1 antibody, hsph1.S antibody, HSPH1 antibody, LOC100546590 antibody, Hsph1 antibody, hsph1.L antibody
    Background

    Description: Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release (PubMed:24318877). Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity).

    Gene: HSPH1

    Molecular Weight
    100kDa
    Gene ID
    10808
    UniProt
    Q92598
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