IGF2 antibody (Internal Region)

Catalog No. ABIN6262492

Product Details anti-IGF2 Antibody

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: IGF2 Antibody detects endogenous levels of total IGF2.

Predicted Reactivity: Pig,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IGF2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for IGF2

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Alternative Name: IGF2 (IGF2 Products)

Synonyms: C11orf43 antibody, IGF-II antibody, PP9974 antibody, LOC100136550 antibody, igf2 antibody, igf2b antibody, wu:fc26e03 antibody, zgc:91781 antibody, igf-2 antibody, insigf antibody, pp9974 antibody, AL033362 antibody, Igf-2 antibody, Igf-II antibody, M6pr antibody, Mpr antibody, Peg2 antibody, IGFII antibody, RNIGF2 antibody, IGF-II-B antibody, igf2-a antibody, igf2-b antibody, insulin like growth factor 2 antibody, insulin-like growth factor II antibody, insulin-like growth factor 2a antibody, insulin like growth factor 2 S homeolog antibody, insulin-like growth factor 2 antibody, insulin-like growth factor 2 (somatomedin A) antibody, insulin like growth factor 2 L homeolog antibody, IGF2 antibody, LOC100136550 antibody, igf2a antibody, igf2.S antibody, Igf2 antibody, igf2.L antibody

Background:

Description: The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling (PubMed:28873464).

Gene: IGF2

Molecular Weight: 20kDa

Gene ID: 3481

UniProt: P01344

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation