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IRF9 antibody (Internal Region)

IRF9 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6262658
  • Target See all IRF9 Antibodies
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Binding Specificity
    • 15
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 49
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 44
    • 6
    • 1
    Rabbit
    Clonality
    • 46
    • 4
    Polyclonal
    Conjugate
    • 26
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRF9 antibody is un-conjugated
    Application
    • 38
    • 15
    • 13
    • 13
    • 10
    • 9
    • 8
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA
    Specificity
    IRF9 Antibody detects endogenous levels of total IRF9.
    Predicted Reactivity
    Horse,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human IRF9, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product IRF9 Primary Antibody
  • Application Notes
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Alternative Name
    IRF9 (IRF9 Products)
    Synonyms
    IRF-9 antibody, ISGF3 antibody, ISGF3G antibody, p48 antibody, zgc:92097 antibody, Irf-9 antibody, Isgf3g antibody, interferon regulatory factor 9 antibody, IRF9 antibody, irf9 antibody, Irf9 antibody
    Background

    Description: Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

    Gene: IRF9

    Molecular Weight
    48 kDa
    Gene ID
    10379
    UniProt
    Q00978
    Pathways
    JAK-STAT Signaling, Interferon-gamma Pathway, Hepatitis C
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