ITPA antibody (Internal Region)

Catalog No. ABIN6262694

Product Details anti-ITPA Antibody

Target: ITPA (Inosine Triphosphatase (ITPA))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: ITPA Antibody detects endogenous levels of total ITPA.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ITPA, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ITPA

Target: ITPA (Inosine Triphosphatase (ITPA))

Alternative Name: ITPA (ITPA Products)

Synonyms: DDBDRAFT_0215619 antibody, DDBDRAFT_0238062 antibody, DDB_0215619 antibody, DDB_0238062 antibody, 2010016I08Rik antibody, AU020102 antibody, Itp antibody, C20orf37 antibody, HLC14-06-P antibody, dJ794I6.3 antibody, ITPase antibody, NTPase antibody, si:ch73-18j6.1 antibody, si:dkey-19f21.1 antibody, inosine triphosphatase antibody, inosine triphosphatase (nucleoside triphosphate pyrophosphatase) antibody, Inosine triphosphate pyrophosphatase antibody, inosine triphosphatase S homeolog antibody, itpa antibody, ITPA antibody, LOC733043 antibody, Itpa antibody, pco148511 antibody, itpa.S antibody

Background:

Description: Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

Gene: ITPA

Molecular Weight: 21kDa

Gene ID: 3704

UniProt: Q9BY32