Kcne3 antibody (Internal Region)

Catalog No. ABIN6262743

Product Details anti-Kcne3 Antibody

Target: Kcne3 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 3 (Kcne3))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kcne3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Specificity: KCNE3 Antibody detects endogenous levels of total KCNE3.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human KCNE3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Kcne3

Target: Kcne3 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 3 (Kcne3))

Alternative Name: KCNE3 (Kcne3 Products)

Synonyms: HOKPP antibody, HYPP antibody, MiRP2 antibody, 2210017H05Rik antibody, potassium voltage-gated channel subfamily E regulatory subunit 3 antibody, potassium voltage-gated channel, Isk-related subfamily, gene 3 antibody, KCNE3 antibody, Kcne3 antibody

Background:

Description: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:12954870). Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship.

Gene: KCNE3

Molecular Weight: 12 kDa

Gene ID: 10008

UniProt: Q9Y6H6