KLHL3 antibody (N-Term)
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- Target See all KLHL3 Antibodies
- KLHL3 (Kelch-Like 3 (KLHL3))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KLHL3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- KLHL3 Antibody detects endogenous levels of total KLHL3.
- Predicted Reactivity
- Bovine,Horse,Sheep,Rabbit
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human KLHL3, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product KLHL3 Primary Antibody
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anti-Kelch-Like 3 (KLHL3) (N-Term) antibody
KLHL3 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 1-301) antibodyKLHL3 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 71-120) antibodyKLHL3 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Rabbit, Horse, Bat, Pig, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 51-160) antibodyKLHL3 Reactivity: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 207-234) antibodyKLHL3 Reactivity: Human WB Host: Rabbit Polyclonal RB37267 unconjugated
anti-Kelch-Like 3 (KLHL3) antibodyKLHL3 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (N-Term) antibodyKLHL3 Reactivity: Human, Cow, Guinea Pig, Rabbit, Bat WB Host: Rabbit Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 1-301) antibodyKLHL3 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (C-Term) antibodyKLHL3 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Pig, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 1-110) antibodyKLHL3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- KLHL3 (Kelch-Like 3 (KLHL3))
- Alternative Name
- KLHL3 (KLHL3 Products)
- Background
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Description: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron (PubMed:14528312, PubMed:22406640, PubMed:23387299, PubMed:23453970, PubMed:23576762, PubMed:23665031). The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation (PubMed:23387299, PubMed:23453970, PubMed:23576762, PubMed:23665031). The BCR(KLHL3) complex also mediates ubiquitination and degradation of CLDN8, a tight-junction protein required for paracellular chloride transport in the kidney (By similarity).
Gene: KLHL3
- Molecular Weight
- 64 kDa
- Gene ID
- 26249
- UniProt
- Q9UH77
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