LPCAT1 antibody (Internal Region)

Catalog No. ABIN6262997

Product Details anti-LPCAT1 Antibody

Target: LPCAT1 (Lysophosphatidylcholine Acyltransferase 1 (LPCAT1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPCAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: LPCAT1 Antibody detects endogenous levels of total LPCAT1.

Predicted Reactivity: Zebrafish,Bovine,Horse,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human LPCAT1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for LPCAT1

Target: LPCAT1 (Lysophosphatidylcholine Acyltransferase 1 (LPCAT1))

Alternative Name: LPCAT1 (LPCAT1 Products)

Synonyms: AYTL2 antibody, Aytl2 antibody, RGD1311599 antibody, PFAAP3 antibody, lpcat antibody, si:dkey-261i16.4 antibody, zgc:158232 antibody, 2900035H07Rik antibody, BB137372 antibody, BC005662 antibody, C87117 antibody, LPCAT antibody, rd11 antibody, lysophosphatidylcholine acyltransferase 1 antibody, LPCAT1 antibody, Lpcat1 antibody, lpcat1 antibody

Background:

Description: Possesses both acyltransferase and acetyltransferase activities (PubMed:16864775, PubMed:21498505). Activity is calcium-independent (By similarity). Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC) (PubMed:21498505). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (PubMed:16704971). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (PubMed:16864775). Involved in the regulation of lipid droplet number and size (PubMed:25491198).

Gene: LPCAT1

Molecular Weight: 59 kDa

Gene ID: 79888

UniProt: Q8NF37