MAGI2 antibody (N-Term)

Catalog No. ABIN6263081

Product Details anti-MAGI2 Antibody

Target: MAGI2 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 2 (MAGI2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGI2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: MAGI2 Antibody detects endogenous levels of total MAGI2.

Predicted Reactivity: Pig,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MAGI2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MAGI2

Target: MAGI2 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 2 (MAGI2))

Alternative Name: MAGI2 (MAGI2 Products)

Synonyms: MAGI2 antibody, si:dkey-97c7.1 antibody, si:dkeyp-86a5.1 antibody, ACVRIP1 antibody, AIP-1 antibody, AIP1 antibody, ARIP1 antibody, MAGI-2 antibody, SSCAM antibody, Acvri1 antibody, Acvrinp1 antibody, Acvrip1 antibody, Magi-2 antibody, S-SCAM antibody, mKIAA0705 antibody, membrane associated guanylate kinase, WW and PDZ domain containing 2 antibody, membrane associated guanylate kinase, WW and PDZ domain containing 2a antibody, MAGI2 antibody, magi2a antibody, magi2 antibody, Magi2 antibody

Background:

Description: Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.

Gene: MAGI2

Molecular Weight: 159kDa

Gene ID: 9863

UniProt: Q86UL8

Pathways: Neurotrophin Signaling Pathway