MAGT1 antibody (Internal Region)

Catalog No. ABIN6263082

Product Details anti-MAGT1 Antibody

Target: MAGT1 (Magnesium Transporter 1 (MAGT1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: MAGT1 Antibody detects endogenous levels of total MAGT1.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MAGT1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MAGT1

Target: MAGT1 (Magnesium Transporter 1 (MAGT1))

Alternative Name: MAGT1 (MAGT1 Products)

Synonyms: IAP antibody, MRX95 antibody, OST3B antibody, PRO0756 antibody, XMEN antibody, bA217H1.1 antibody, 2410001C15Rik antibody, 2610529C04Rik antibody, 2810482I07Rik antibody, IAG2 antibody, Iag2 antibody, magnesium transporter 1 antibody, MAGT1 antibody, Magt1 antibody

Background:

Description: Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues, in this function seems to act redundantly with TUSC3. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition.

Gene: MAGT1

Molecular Weight: 45-47 kDa

Gene ID: 84061

UniProt: Q9H0U3

Pathways: Cell RedoxHomeostasis