MCM10 antibody (C-Term)

Catalog No. ABIN6263157

Product Details anti-MCM10 Antibody

Target: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: MCM10 Antibody detects endogenous levels of total MCM10.

Predicted Reactivity: Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MCM10, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MCM10

Target: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Alternative Name: MCM10 (MCM10 Products)

Synonyms: CG9241 antibody, DmMCM10 antibody, Dmel\\CG9241 antibody, Scim19 antibody, mcm10 antibody, CNA43 antibody, DNA43 antibody, xmcm10 antibody, 2410041F14Rik antibody, AU018508 antibody, C330019M07Rik antibody, C79164 antibody, Minichromosome maintenance 10 antibody, minichromosome maintenance 10 replication initiation factor antibody, minichromosome maintenance 10 replication initiation factor L homeolog antibody, Mcm10 antibody, MCM10 antibody, mcm10.L antibody

Background:

Description: Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability, acts as a direct target of transcriptional repression by ZBTB38 (PubMed:24726359).

Gene: MCM10

Molecular Weight: 97-105 kDa

Gene ID: 55388

UniProt: Q7L590

Pathways: Mitotic G1-G1/S Phases, DNA Replication