MED22 antibody (Internal Region)

Catalog No. ABIN6263192

Product Details anti-MED22 Antibody

Target: MED22 (Mediator Complex Subunit 22 (MED22))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED22 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: MED22 Antibody detects endogenous levels of total MED22.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MED22, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MED22

Target: MED22 (Mediator Complex Subunit 22 (MED22))

Alternative Name: MED22 (MED22 Products)

Synonyms: MED24 antibody, SURF5 antibody, surf-5 antibody, AW212655 antibody, AW558812 antibody, Surf-5 antibody, Surf5 antibody, 144358_at antibody, CG18830 antibody, CG3034 antibody, Dmel\\CG3034 antibody, EG:BACR7A4.6 antibody, Med22 antibody, Med24 antibody, Srb6/Surf5 antibody, anon-EST:Liang-1.82 antibody, clone 1.82 antibody, dMED24 antibody, si:ch73-278c20.1 antibody, si:dkey-226m8.2 antibody, surf5 antibody, wu:fj45h07 antibody, zgc:86721 antibody, Surf5b antibody, MGC80238 antibody, RGD1564893 antibody, mediator complex subunit 22 antibody, Mediator complex subunit 22 antibody, mediator complex subunit 22 L homeolog antibody, MED22 antibody, Med22 antibody, med22 antibody, med22.L antibody

Background:

Description: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Gene: MED22

Molecular Weight: 22 kDa

Gene ID: 6837

UniProt: Q15528

Pathways: Regulation of Lipid Metabolism by PPARalpha