CCL3 antibody (Internal Region)

Catalog No. ABIN6263256

Product Details anti-CCL3 Antibody

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: MIP-1 alpha Antibody detects endogenous levels of total MIP-1 alpha.

Predicted Reactivity: Bovine,Horse

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MIP-1 alpha, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CCL3

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Alternative Name: CCL3 (CCL3 Products)

Synonyms: MIP-1alpha antibody, G0S19-1 antibody, LD78ALPHA antibody, MIP-1-alpha antibody, MIP1A antibody, SCYA3 antibody, MIP-1a antibody, Scya3 antibody, AI323804 antibody, LD78alpha antibody, MIP1-(a) antibody, MIP1-alpha antibody, Mip1a antibody, CCL3L1 antibody, CCL3L3 antibody, chemokine (C-C motif) ligand 3 antibody, C-C motif chemokine ligand 3 antibody, CCL3 antibody, Ccl3 antibody

Background:

Description: Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

Gene: CCL3

Molecular Weight: 10 kDa

Gene ID: 6348

UniProt: P10147

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagy