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MORF4L1 antibody (N-Term)

MORF4L1 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6263328
  • Target See all MORF4L1 Antibodies
    MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))
    Binding Specificity
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 42
    • 42
    • 21
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 53
    • 3
    • 2
    Rabbit
    Clonality
    • 55
    • 3
    Polyclonal
    Conjugate
    • 29
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MORF4L1 antibody is un-conjugated
    Application
    • 42
    • 15
    • 14
    • 14
    • 11
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    MORF4L1 Antibody detects endogenous levels of total MORF4L1.
    Predicted Reactivity
    Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MORF4L1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MORF4L1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))
    Alternative Name
    MORF4L1 (MORF4L1 Products)
    Synonyms
    Eaf3 antibody, HsT17725 antibody, MEAF3 antibody, MORFRG15 antibody, MRG15 antibody, S863-6 antibody, TEG-189 antibody, Tex189 antibody, mKIAA4002 antibody, MORF4L2 antibody, CG6363 antibody, DmMRG15 antibody, Dmel\\CG6363 antibody, Dmrg15 antibody, Mrg15 antibody, dMRG15 antibody, dMrg15 antibody, l(3)j6A3 antibody, zgc:92289 antibody, mortality factor 4 like 1 antibody, MORF-related gene 15 antibody, MRG15 antibody, mortality factor 4 like 1 S homeolog antibody, MORF4L1 antibody, Morf4l1 antibody, MRG15 antibody, CpipJ_CPIJ013367 antibody, morf4l1.S antibody, morf4l1 antibody
    Background

    Description: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci.

    Gene: MORF4L1

    Molecular Weight
    41kDa
    Gene ID
    10933
    UniProt
    Q9UBU8
    Pathways
    Chromatin Binding
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