MT-ATP6 antibody (Internal Region)

Catalog No. ABIN6263407

Product Details anti-MT-ATP6 Antibody

Target: MT-ATP6 (Mitochondrially Encoded ATP Synthase 6 (MT-ATP6))

Binding Specificity: Internal Region

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MT-ATP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: MT-ATP6 Antibody detects endogenous levels of total MT-ATP6.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MT-ATP6, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MT-ATP6

Target: MT-ATP6 (Mitochondrially Encoded ATP Synthase 6 (MT-ATP6))

Alternative Name: MT-ATP6 (MT-ATP6 Products)

Synonyms: mtatp6 antibody, ATPase6 antibody, MTATP6 antibody, ATPase 6 antibody, ATP antibody, ATPIB antibody, CAMRQ4 antibody, IB antibody, ML-1 antibody, ATP synthase 6 antibody, ATP synthase F0 subunit 6 antibody, ATPase phospholipid transporting 8A2 antibody, ATPase subunit 6 antibody, H(+)-transporting ATPasesubunit 6 antibody, ATP6 antibody, ATP8A2 antibody, atp6 antibody

Background:

Description: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel, it may play a direct role in the translocation of protons across the membrane.

Gene: MT-ATP6

Molecular Weight: 25 kDa

Gene ID: 4508

UniProt: P00846

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process