MYOD1 antibody (Internal Region)

Catalog No. ABIN6263488

Product Details anti-MYOD1 Antibody

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYOD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: MyoD1 Antibody detects endogenous levels of total MyoD1.

Predicted Reactivity: Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MyoD1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MYOD1

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Alternative Name: MYOD1 (MYOD1 Products)

Synonyms: MYF3 antibody, MYOD antibody, PUM antibody, bHLHc1 antibody, MyoD antibody, XMyoD antibody, XtmyoD antibody, mf25 antibody, myf3 antibody, pum antibody, MUF3 antibody, AI503393 antibody, Myod-1 antibody, etID309723.25 antibody, myod antibody, wu:fb57a01 antibody, zgc:136744 antibody, MYOD1 antibody, myod1 antibody, mf1 antibody, myod1-a antibody, myod1-b antibody, myogenic differentiation 1 antibody, MYOD protein antibody, myogenic factor MyoD1 antibody, myogenic differentiation 1 S homeolog antibody, myogenic differentiation 1 L homeolog antibody, MYOD1 antibody, myod1 antibody, Myod1 antibody, myod antibody, myod1.S antibody, myod1.L antibody

Background:

Description: Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).

Gene: MYOD1

Molecular Weight: 45 kDa

Gene ID: 4654

UniProt: P15172

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development