NAMPT antibody (C-Term)

Catalog No. ABIN6263511

Product Details anti-NAMPT Antibody

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAMPT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: NAMPT Antibody detects endogenous levels of total NAMPT.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NAMPT, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Alternative Name: NAMPT (NAMPT Products)

Synonyms: 1110035O14Rik antibody, PBEF antibody, PBEF1 antibody, VF antibody, VISFATIN antibody, AI314458 antibody, AI480535 antibody, NAmPRTase antibody, Pbef antibody, Pbef1 antibody, Visfatin antibody, visfatin antibody, pbef antibody, pbef1 antibody, nicotinamide phosphoribosyltransferase antibody, Nicotinamide phosphoribosyltransferase antibody, nicotinamide phosphoribosyltransferase S homeolog antibody, NAMPT antibody, Nampt antibody, nampt antibody, Smon_0680 antibody, Mrub_2845 antibody, Cseg_3704 antibody, BC1002_3997 antibody, Ftrac_2686 antibody, Varpa_5681 antibody, Celal_3900 antibody, Deima_0880 antibody, BC1001_3724 antibody, Celly_1696 antibody, Clole_1542 antibody, Tsp_05934 antibody, nampt.S antibody

Background:

Description: Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).

Gene: NAMPT

Molecular Weight: 52kDa

Gene ID: 10135

UniProt: P43490