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Neuropilin 1 antibody

NRP1 Reactivity: Human, Rat, Mouse WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6263738
  • Target See all Neuropilin 1 (NRP1) Antibodies
    Neuropilin 1 (NRP1)
    Reactivity
    • 105
    • 59
    • 49
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 105
    • 24
    • 4
    • 2
    Rabbit
    Clonality
    • 99
    • 36
    Polyclonal
    Conjugate
    • 57
    • 21
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Neuropilin 1 antibody is un-conjugated
    Application
    • 100
    • 44
    • 38
    • 27
    • 17
    • 15
    • 14
    • 12
    • 10
    • 8
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificity
    NRP1 Antibody detects endogenous levels of total NRP1
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human NRP1
    Isotype
    IgG
    Top Product
    Discover our top product NRP1 Primary Antibody
  • Application Notes
    WB 1:1000-3000 IHC 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    Neuropilin 1 (NRP1)
    Alternative Name
    NRP1 (NRP1 Products)
    Synonyms
    NRP1 antibody, cd304 antibody, neuropilin antibody, np-1 antibody, npn-1 antibody, nrp antibody, nrp-1 antibody, vegf165r antibody, BDCA4 antibody, CD304 antibody, NP1 antibody, NRP antibody, VEGF165R antibody, C530029I03 antibody, NP-1 antibody, NPN-1 antibody, Npn1 antibody, Nrp antibody, neuropilin 1 antibody, neuropilin 1 L homeolog antibody, NRP1 antibody, nrp1 antibody, Nrp1 antibody, nrp1.L antibody
    Background

    Description: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulate VEGF-induced angiogenesis. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity).

    Gene: NRP1

    Molecular Weight
    103 kDa
    Gene ID
    8829
    UniProt
    O14786
    Pathways
    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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