Plexin A2 antibody (Internal Region)

Catalog No. ABIN6264313

Product Details anti-Plexin A2 Antibody

Target: Plexin A2 (Plxna2)

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plexin A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: PLXNA2 Antibody detects endogenous levels of total PLXNA2.

Predicted Reactivity: Pig,Zebrafish,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PLXNA2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Plexin A2

Target: Plexin A2 (Plxna2)

Alternative Name: PLXNA2 (Plxna2 Products)

Synonyms: oct antibody, plxn2 antibody, OCT antibody, PLXN2 antibody, 2810428A13Rik antibody, AA589422 antibody, AW457381 antibody, Plxn2 antibody, mKIAA0463 antibody, plexin A2 antibody, plexin-A2 antibody, PLXNA2 antibody, plxna2 antibody, LOC100078346 antibody, Plxna2 antibody

Background:

Description: Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).

Gene: PLXNA2

Molecular Weight: 211kDa

Gene ID: 5362

UniProt: O75051