POFUT2 antibody (Internal Region)

Catalog No. ABIN6264330

Product Details anti-POFUT2 Antibody

Target: POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POFUT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: POFUT2 Antibody detects endogenous levels of total POFUT2.

Predicted Reactivity: Pig,Zebrafish,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human POFUT2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200, WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for POFUT2

Target: POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

Alternative Name: POFUT2 (POFUT2 Products)

Synonyms: C21orf80 antibody, FUT13 antibody, fc46a11 antibody, wu:fc46a11 antibody, zgc:194822 antibody, 2310011G23Rik antibody, AI256847 antibody, BC003494 antibody, protein O-fucosyltransferase 2 antibody, POFUT2 antibody, pofut2 antibody, Pofut2 antibody

Background:

Description: Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X2-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and localization of the definite endoderm (By similarity). Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13.

Gene: POFUT2

Molecular Weight: 49kDa

Gene ID: 23275

UniProt: Q9Y2G5