POLR2L antibody (Internal Region)

Catalog No. ABIN6264348

Product Details anti-POLR2L Antibody

Target: POLR2L (Polymerase (RNA) II (DNA Directed) Polypeptide L, 7.6kDa (POLR2L))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR2L antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Specificity: POLR2L Antibody detects endogenous levels of total POLR2L.

Predicted Reactivity: Pig,Zebrafish,Bovine,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human POLR2L, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for POLR2L

Target: POLR2L (Polymerase (RNA) II (DNA Directed) Polypeptide L, 7.6kDa (POLR2L))

Alternative Name: POLR2L (POLR2L Products)

Synonyms: BcDNA:SD08670 antibody, CG13628 antibody, Dmel\\CG13628 antibody, RPB10 antibody, hrpb7.6 antibody, hsrpb10b antibody, polr2l antibody, rbp10 antibody, rpabc5 antibody, rpb10 antibody, rpb10beta antibody, rpb7.6 antibody, 2510029B14Rik antibody, RBP10 antibody, RPABC5 antibody, RPB10beta antibody, RPB7.6 antibody, hRPB7.6 antibody, CG13628 gene product from transcript CG13628-RA antibody, polymerase (RNA) II subunit L antibody, polymerase (RNA) II subunit L L homeolog antibody, RNA polymerase II subunit L antibody, polymerase (RNA) II (DNA directed) polypeptide L antibody, DNA-directed RNA polymerases I, II, and III subunit RPABC5 antibody, Rpb10 antibody, polr2l.1 antibody, polr2l.1.L antibody, POLR2L antibody, Polr2l antibody, rpb-10 antibody

Background:

Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2L/RBP10 is part of the core element with the central large cleft (By similarity).

Gene: POLR2L

Molecular Weight: 7kDa

Gene ID: 5441

UniProt: P62875

Pathways: Regulatory RNA Pathways