PPM1E antibody (Internal Region)

Catalog No. ABIN6264378

Product Details anti-PPM1E Antibody

Target: PPM1E (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1E (PPM1E))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPM1E antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Specificity: PPM1E Antibody detects endogenous levels of total PPM1E.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PPM1E, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PPM1E

Target: PPM1E (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1E (PPM1E))

Alternative Name: PPM1E (PPM1E Products)

Synonyms: AW049266 antibody, B930008A12Rik antibody, POPX1 antibody, PP2CH antibody, mKIAA1072 antibody, CaMKP-N antibody, caMKN antibody, protein phosphatase 1E (PP2C domain containing) antibody, protein phosphatase, Mg2+/Mn2+ dependent 1E antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1E antibody, Ppm1e antibody, PPM1E antibody

Background:

Description: Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2 (By similarity). Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2 (By similarity).

Gene: PPM1E

Molecular Weight: 85 kDa

Gene ID: 22843

UniProt: Q8WY54