PTPRK antibody (Internal Region)

Catalog No. ABIN6264523

Product Details anti-PTPRK Antibody

Target: PTPRK (Protein Tyrosine Phosphatase Receptor Type K (PTPRK))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: PTPRK Antibody detects endogenous levels of total PTPRK.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PTPRK, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PTPRK

Target: PTPRK (Protein Tyrosine Phosphatase Receptor Type K (PTPRK))

Alternative Name: PTPRK (PTPRK Products)

Synonyms: R-PTP-kappa antibody, Rptpk antibody, AI853699 antibody, PTPk antibody, RPTPkappa antibody, protein tyrosine phosphatase, receptor type K antibody, protein tyrosine phosphatase, receptor type, K antibody, PTPRK antibody, Ptprk antibody

Background:

Description: Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa.

Gene: PTPRK

Molecular Weight: 162 kDa

Gene ID: 5796

UniProt: Q15262

Pathways: Cell-Cell Junction Organization