POLR3K antibody (Internal Region)
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- Target See all POLR3K Antibodies
- POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POLR3K antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- RPC10 Antibody detects endogenous levels of total RPC10.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RPC10, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product POLR3K Primary Antibody
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- Application Notes
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
- Alternative Name
- POLR3K (POLR3K Products)
- Synonyms
- MGC108467 antibody, POLR3K antibody, 12.3kDa antibody, 1500004O14Rik antibody, AI196849 antibody, AU014893 antibody, C11 antibody, RPC10 antibody, RPC11 antibody, C11-RNP3 antibody, RPC12.5 antibody, hRPC11 antibody, RNA polymerase III subunit K antibody, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa S homeolog antibody, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa antibody, polymerase (RNA) III (DNA directed) polypeptide K antibody, Polr3k antibody, polr3k.S antibody, polr3k antibody, POLR3K antibody
- Background
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Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Gene: POLR3K
- Molecular Weight
- 12 kDa
- Gene ID
- 51728
- UniProt
- Q9Y2Y1
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