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POLR3K antibody (Internal Region)

POLR3K Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6264820
  • Target See all POLR3K Antibodies
    POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
    Binding Specificity
    • 10
    • 1
    • 1
    Internal Region
    Reactivity
    • 29
    • 9
    • 9
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 24
    • 5
    Rabbit
    Clonality
    • 26
    • 3
    Polyclonal
    Conjugate
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This POLR3K antibody is un-conjugated
    Application
    • 12
    • 9
    • 5
    • 2
    Western Blotting (WB), ELISA
    Specificity
    RPC10 Antibody detects endogenous levels of total RPC10.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RPC10, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product POLR3K Primary Antibody
  • Application Notes
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
    Alternative Name
    POLR3K (POLR3K Products)
    Synonyms
    MGC108467 antibody, POLR3K antibody, 12.3kDa antibody, 1500004O14Rik antibody, AI196849 antibody, AU014893 antibody, C11 antibody, RPC10 antibody, RPC11 antibody, C11-RNP3 antibody, RPC12.5 antibody, hRPC11 antibody, RNA polymerase III subunit K antibody, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa S homeolog antibody, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa antibody, polymerase (RNA) III (DNA directed) polypeptide K antibody, Polr3k antibody, polr3k.S antibody, polr3k antibody, POLR3K antibody
    Background

    Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

    Gene: POLR3K

    Molecular Weight
    12 kDa
    Gene ID
    51728
    UniProt
    Q9Y2Y1
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