RXFP1 antibody (Internal Region)

Catalog No. ABIN6264888

Product Details anti-RXFP1 Antibody

Target: RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RXFP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: RXFP1 Antibody detects endogenous levels of total RXFP1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RXFP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for RXFP1

Target: RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))

Alternative Name: RXFP1 (RXFP1 Products)

Synonyms: LGR7 antibody, RXFPR1 antibody, Gm1018 antibody, Lgr7 antibody, RXFP2 antibody, relaxin/insulin like family peptide receptor 1 antibody, relaxin/insulin-like family peptide receptor 1 antibody, RXFP1 antibody, rxfp1 antibody, Rxfp1 antibody

Background:

Description: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.

Gene: RXFP1

Molecular Weight: 87kDa

Gene ID: 59350

UniProt: Q9HBX9

Pathways: Myometrial Relaxation and Contraction