RYK antibody (Internal Region)
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- Target See all RYK Antibodies
- RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RYK antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- RYK Antibody detects endogenous levels of total RYK.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RYK, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product RYK Primary Antibody
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- Application Notes
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
- Alternative Name
- RYK (RYK Products)
- Synonyms
- RYK antibody, jtk5 antibody, ryk1 antibody, jtk5a antibody, d3s3195 antibody, wu:fb37b12 antibody, wu:fi05b06 antibody, zgc:158381 antibody, MGC114645 antibody, D3S3195 antibody, JTK5 antibody, JTK5A antibody, RYK1 antibody, AW536699 antibody, ERK-3 antibody, Vik antibody, receptor-like tyrosine kinase antibody, receptor-like tyrosine kinase S homeolog antibody, tyrosine-protein kinase RYK antibody, RYK antibody, ryk antibody, ryk.S antibody, LOC100541106 antibody, Ryk antibody
- Background
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Description: May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Gene: RYK
- Molecular Weight
- 68 kDa
- Gene ID
- 6259
- UniProt
- P34925
- Pathways
- RTK Signaling, WNT Signaling, Regulation of Cell Size
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