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SREBF2 antibody (Internal Region)

SREBF2 Reactivity: Human, Rat, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265283
  • Target See all SREBF2 Antibodies
    SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))
    Binding Specificity
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 65
    • 31
    • 30
    • 15
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 58
    • 7
    • 1
    Rabbit
    Clonality
    • 60
    • 6
    Polyclonal
    Conjugate
    • 31
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SREBF2 antibody is un-conjugated
    Application
    • 51
    • 28
    • 21
    • 18
    • 11
    • 9
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    SREBP2 Antibody detects endogenous levels of total SREBP2.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human SREBP2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product SREBF2 Primary Antibody
  • Application Notes
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))
    Alternative Name
    SREBF2 (SREBF2 Products)
    Synonyms
    SREBF2 antibody, srebp2 antibody, SREBP2 antibody, zgc:158371 antibody, AI608257 antibody, SREBP-2 antibody, SREBP2gc antibody, bHLHd2 antibody, lop13 antibody, nuc antibody, Srebf2_retired antibody, sterol regulatory element binding transcription factor 2 antibody, sterol regulatory element binding factor 2 antibody, sterol regulatory element binding transcription factor 2 L homeolog antibody, SREBF2 antibody, srebf2 antibody, Srebf2 antibody, srebf2.L antibody
    Background

    Description: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.

    Gene: SREBF2

    Molecular Weight
    124kDa
    Gene ID
    6721
    UniProt
    Q12772
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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