SNCAIP antibody (Internal Region)

Catalog No. ABIN6265402

Product Details anti-SNCAIP Antibody

Target: SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNCAIP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: Synphilin-1 Antibody detects endogenous levels of total Synphilin-1.

Predicted Reactivity: Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Synphilin-1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SNCAIP

Target: SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))

Alternative Name: SNCAIP (SNCAIP Products)

Synonyms: sncaip antibody, MGC88953 antibody, SNCAIP antibody, LOC100221074 antibody, SYPH1 antibody, Sph1 antibody, Syph1 antibody, 2810407O15Rik antibody, 4933427B05Rik antibody, BB104594 antibody, synuclein alpha interacting protein antibody, synuclein, alpha interacting protein antibody, synuclein, alpha interacting protein (synphilin) antibody, SNCAIP antibody, sncaip antibody, Sncaip antibody

Background:

Description: Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1.

Gene: SNCAIP

Molecular Weight: 100 kDa

Gene ID: 9627

UniProt: Q9Y6H5