TNFAIP8 antibody (Internal Region)

Catalog No. ABIN6265541

Product Details anti-TNFAIP8 Antibody

Target: TNFAIP8 (Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFAIP8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: TFIP8 Antibody detects endogenous levels of total TFIP8.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TFIP8, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TNFAIP8

Target: TNFAIP8 (Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8))

Alternative Name: TNFAIP8 (TNFAIP8 Products)

Synonyms: MGC55331 antibody, zgc:55331 antibody, si:dkey-49m19.6 antibody, GG2-1 antibody, MDC-3.13 antibody, SCC-S2 antibody, SCCS2 antibody, AA987150 antibody, E130304C20Rik antibody, ENSMUSG00000073567 antibody, Gg2-1 antibody, Gm10539 antibody, Nded antibody, Ssc-2 antibody, tumor necrosis factor, alpha-induced protein 8-like 1 antibody, TNF alpha induced protein 8 S homeolog antibody, TNF alpha induced protein 8 antibody, tumor necrosis factor, alpha-induced protein 8 antibody, tnfaip8l1 antibody, tnfaip8.S antibody, TNFAIP8 antibody, Tnfaip8 antibody

Background:

Description: Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

Gene: TNFAIP8

Molecular Weight: 23kDa

Gene ID: 25816

UniProt: O95379