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TRAF1 antibody (C-Term)

TRAF1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265702
  • Target See all TRAF1 Antibodies
    TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 50
    • 30
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 42
    • 10
    • 1
    Rabbit
    Clonality
    • 45
    • 8
    Polyclonal
    Conjugate
    • 29
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRAF1 antibody is un-conjugated
    Application
    • 34
    • 22
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    TRAF1 Antibody detects endogenous levels of total TRAF1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TRAF1, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product TRAF1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
    Alternative Name
    TRAF1 (TRAF1 Products)
    Synonyms
    CG3048 antibody, DTRAF antibody, DTRAF1 antibody, Dmel\\CG3048 antibody, TRAF antibody, TRAF1 antibody, Traf1 antibody, dTRAF antibody, dTRAF1 antibody, dTraf1 antibody, dtraf1 antibody, traf1 antibody, traf4 antibody, DKFZp469G032 antibody, EBI6 antibody, MGC:10353 antibody, 4732496E14Rik antibody, TNF receptor associated factor 1 antibody, TNF-receptor-associated factor 4 antibody, TNF receptor-associated factor 1 antibody, TRAF1 antibody, Traf4 antibody, Traf1 antibody, traf1 antibody
    Background

    Description: Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.

    Gene: TRAF1

    Molecular Weight
    46 kDa
    Gene ID
    7185
    UniProt
    Q13077
    Pathways
    NF-kappaB Signaling, Apoptosis, Cell-Cell Junction Organization, Asymmetric Protein Localization
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