TRIM38 antibody (Internal Region)

Catalog No. ABIN6265738

Product Details anti-TRIM38 Antibody

Target: TRIM38 (Tripartite Motif Containing 38 (TRIM38))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM38 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: TRIM38 Antibody detects endogenous levels of total TRIM38.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TRIM38, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TRIM38

Target: TRIM38 (Tripartite Motif Containing 38 (TRIM38))

Alternative Name: TRIM38 (TRIM38 Products)

Synonyms: TRIM38 antibody, RNF15 antibody, RORET antibody, Gm23 antibody, tripartite motif containing 38 antibody, tripartite motif-containing 38 antibody, TRIM38 antibody, Trim38 antibody

Background:

Description: E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling.

Gene: TRIM38

Molecular Weight: 53kDa

Gene ID: 10475

UniProt: O00635