TSC22D3 antibody (Internal Region)

Catalog No. ABIN6265764

Product Details anti-TSC22D3 Antibody

Target: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSC22D3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: TSC-22R Antibody detects endogenous levels of total TSC-22R.

Predicted Reactivity: Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TSC-22R, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TSC22D3

Target: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Alternative Name: TSC22D3 (TSC22D3 Products)

Synonyms: dsipi antibody, MGC53285 antibody, zgc:65831 antibody, zgc:77028 antibody, TSC22D3 antibody, GILZ antibody, gilz antibody, tsc-22r antibody, DIP antibody, DSIPI antibody, TSC-22R antibody, hDIP antibody, Dsip1 antibody, Gilz antibody, Tilz3 antibody, Dsipi antibody, DSIP antibody, TSC22 domain family member 3 L homeolog antibody, TSC22 domain family, member 3 antibody, TSC22 domain family member 3 antibody, tsc22d3.L antibody, tsc22d3 antibody, TSC22D3 antibody, Tsc22d3 antibody

Background:

Description: Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (By similarity). Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG (By similarity).

Gene: TSC22D3

Molecular Weight: 15 kDa

Gene ID: 1831

UniProt: Q99576