USP46 antibody (Internal Region)

Catalog No. ABIN6265929

Product Details anti-USP46 Antibody

Target: USP46 (Ubiquitin Specific Peptidase 46 (USP46))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP46 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: USP46 Antibody detects endogenous levels of total USP46.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human USP46, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for USP46

Target: USP46 (Ubiquitin Specific Peptidase 46 (USP46))

Alternative Name: USP46 (USP46 Products)

Synonyms: RGD1564808 antibody, usp46 antibody, MGC53480 antibody, 1190009E20Rik antibody, 2410018I08Rik antibody, AI451644 antibody, si:ch73-16a12.1 antibody, ubiquitin specific peptidase 46 antibody, ubiquitin specific peptidase 46 S homeolog antibody, Usp46 antibody, usp46.S antibody, USP46 antibody, usp46 antibody

Background:

Description: Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67 (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:19075014, PubMed:26388029). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014).

Gene: USP46

Molecular Weight: 42 kDa

Gene ID: 64854

UniProt: P62068