WDR18 antibody (Internal Region)

Catalog No. ABIN6266019

Product Details anti-WDR18 Antibody

Target: WDR18 (WD Repeat Domain 18 (WDR18))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR18 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: WDR18 Antibody detects endogenous levels of total WDR18.

Predicted Reactivity: Pig,Bovine,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human WDR18, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for WDR18

Target: WDR18 (WD Repeat Domain 18 (WDR18))

Alternative Name: WDR18 (WDR18 Products)

Synonyms: Ipi3 antibody, R32184_1 antibody, 2310012I10Rik antibody, AU044733 antibody, AW122032 antibody, WD repeat domain 18 antibody, WDR18 antibody, Wdr18 antibody

Background:

Description: Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859). Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (PubMed:21326211).

Gene: WDR18

Molecular Weight: 47 kDa

Gene ID: 57418

UniProt: Q9BV38