WNT2 antibody (Internal Region)

Catalog No. ABIN6266039

Product Details anti-WNT2 Antibody

Target: WNT2 (Wingless-Type MMTV Integration Site Family Member 2 (WNT2))

Binding Specificity: Internal Region

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: WNT2 Antibody detects endogenous levels of total WNT2.

Predicted Reactivity: Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human WNT2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for WNT2

Target: WNT2 (Wingless-Type MMTV Integration Site Family Member 2 (WNT2))

Alternative Name: WNT2 (WNT2 Products)

Synonyms: CG1916 antibody, D-wnt-2 antibody, DWnt-2 antibody, DWnt2 antibody, Dm DWnt2 antibody, Dm-2 antibody, Dmel\\CG1916 antibody, Dwnt-2 antibody, Wnt antibody, Wnt-2 antibody, dWnt2 antibody, wnt2 antibody, WNT2 antibody, irp antibody, Xwnt2 antibody, wnt-2 antibody, Xwnt-2 antibody, int1l1 antibody, 2610510E18Rik antibody, Int1l1 antibody, Irp antibody, Mirp antibody, Wnt2a antibody, INT1L1 antibody, IRP antibody, ZfWnt2 antibody, Wnt oncogene analog 2 antibody, Wnt family member 2 antibody, wingless-type MMTV integration site family member 2 antibody, wingless-type MMTV integration site family, member 2 antibody, Wnt2 antibody, wnt2 antibody, WNT2 antibody

Background:

Description: Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:20018874). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity).

Gene: WNT2

Molecular Weight: 40 kDa

Gene ID: 7472

UniProt: P09544

Pathways: WNT Signaling