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MYT1 antibody (Myelin Transcription Factor 1) (pSer120) Primary Antibody

MYT1 Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6270282
$450.00
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  • Target
    MYT1
    Binding Specificity
    • 16
    • 15
    • 15
    • 9
    • 9
    • 9
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer120
    Reactivity
    • 78
    • 22
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 90
    • 4
    Rabbit
    Clonality
    • 93
    • 1
    Polyclonal
    Conjugate
    • 33
    • 9
    • 7
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYT1 antibody is un-conjugated
    Application
    • 66
    • 54
    • 19
    • 14
    • 14
    • 9
    • 7
    • 4
    • 2
    • 2
    • 2
    ELISA, Western Blotting (WB)
    Specificity
    Phospho-Myt1 (Ser120) Antibody detects endogenous levels of Myt1 only when phosphorylated at Ser120
    Cross-Reactivity
    Human
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human Myt1 around the phosphorylation site of Ser120
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    MYT1
    Alternative Name
    Myt1 (MYT1 Antibody Abstract)
    Synonyms
    fc56h05, myt1, si:dkey-202m22.5, wu:fc56h05, C20orf36, MTF1, MYTI, PLPB1, ZC2HC4A, Nzf2, Nzf2a, Nzf2b, Nztf2, myelin transcription factor 1, myelin transcription factor 1a, myelin transcription factor 1 S homeolog, MYT1, myt1a, Myt1, myt1.S
    Background

    Description: Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.

    Gene: PKMYT1

    Molecular Weight
    70kDa
    Gene ID
    9088
    UniProt
    Q99640
    Pathways
    Cell Division Cycle
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