PTBP2 antibody (Internal Region)

Catalog No. ABIN6274041

Product Details anti-PTBP2 Antibody

Target: PTBP2 (Polypyrimidine Tract Binding Protein 2 (PTBP2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Specificity: PTBP2 Antibody detects endogenous levels of total PTBP2.

Predicted Reactivity: Pig,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PTBP2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PTBP2

Target: PTBP2 (Polypyrimidine Tract Binding Protein 2 (PTBP2))

Alternative Name: PTBP2 (PTBP2 Products)

Synonyms: PTB antibody, PTBLP antibody, brPTB antibody, nPTB antibody, nPTB5 antibody, nPTB6 antibody, nPTB7 antibody, nPTB8 antibody, Ptb2 antibody, PTBP2 antibody, im:7153495 antibody, ptbp2 antibody, si:ch211-160l17.2 antibody, wu:fa08f05 antibody, wu:fc05d10 antibody, zgc:113074 antibody, polypyrimidine tract binding protein 2 antibody, polypyrimidine tract binding protein 2b antibody, polypyrimidine tract binding protein 2a antibody, PTBP2 antibody, Ptbp2 antibody, ptbp2b antibody, ptbp2a antibody

Background:

Description: RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.

Gene: PTBP2

Molecular Weight: 57kDa

Gene ID: 58155

UniProt: Q9UKA9

Pathways: Ribonucleoprotein Complex Subunit Organization, SARS-CoV-2 Protein Interactome