IL11RA antibody (C-Term)

Catalog No. ABIN6275769

Product Details anti-IL11RA Antibody

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL11RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: IL11RA Antibody detects endogenous levels of total IL11RA.

Predicted Reactivity: Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IL11RA, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for IL11RA

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Alternative Name: IL11RA (IL11RA Products)

Synonyms: CRSDA antibody, fi26e06 antibody, il-11ra antibody, wu:fi26e06 antibody, AI314697 antibody, GP130 antibody, Il-11ra antibody, Il11ra antibody, Il11ra2 antibody, NR1 antibody, interleukin 11 receptor subunit alpha antibody, interleukin 11 receptor, alpha antibody, interleukin 11 receptor subunit alpha 1 antibody, interleukin 11 receptor, alpha chain 1 antibody, IL11RA antibody, il11ra antibody, Il11ra1 antibody, Il11ra antibody

Background:

Description: Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.

Gene: IL11RA

Molecular Weight: 45 kDa

Gene ID: 3590

UniProt: Q14626

Pathways: JAK-STAT Signaling, Growth Factor Binding