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AIRE antibody (Ser156)

AIRE Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6280595
  • Target See all AIRE Antibodies
    AIRE (Autoimmune Regulator (AIRE))
    Binding Specificity
    • 10
    • 9
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-180, Ser156
    Reactivity
    • 51
    • 23
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    Human
    Host
    • 46
    • 7
    • 1
    Rabbit
    Clonality
    • 53
    Polyclonal
    Conjugate
    • 38
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIRE antibody is un-conjugated
    Application
    • 39
    • 24
    • 19
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purpose
    Rabbit polyclonal to AIRE-1.
    Specificity
    AIRE-1 Polyclonal Antibody detects endogenous levels of AIRE-1 protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156.
    Isotype
    IgG
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    Discover our top product AIRE Primary Antibody
  • Application Notes
    WB 1:500-1:2000
    ELISA 1:5000
    Comment

    Widely expressed. Expressed at higher level in thymus (medullary epithelial cells and monocyte-dendritic cells), pancreas, adrenal cortex and testis. Expressed at lower level in the spleen, fetal liver and lymph nodes. In secondary lymphoid organs, expressed in a discrete population of bone marrow-derived toleregenic antigen presenting cells (APCs) called extrathymic AIRE expressing cells (eTAC)(at protein level) . Isoform 2 and isoform 3 seem to be less frequently expressed than isoform 1, if at all.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • Target
    AIRE (Autoimmune Regulator (AIRE))
    Alternative Name
    AIRE-1 (AIRE Products)
    Synonyms
    AIRE1 antibody, APECED antibody, APS1 antibody, APSI antibody, PGA1 antibody, autoimmune regulator antibody, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antibody, AaeL_AAEL013794 antibody, CpipJ_CPIJ001208 antibody, CpipJ_CPIJ001209 antibody, AIRE antibody, Aire antibody
    Molecular Weight
    50 kDa
    Gene ID
    326
    UniProt
    O43918
    Pathways
    Chromatin Binding
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