VAV3 antibody (pTyr173)

Catalog No. ABIN6280921

Product Details anti-VAV3 Antibody

Target: VAV3 (Vav 3 Oncogene (VAV3))

Binding Specificity: AA 110-190, pTyr173

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAV3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal to Phospho-Vav3 (Y173).

Specificity: Phospho-Vav3 (Y173) Polyclonal Antibody detects endogenous levels of Vav3 protein only when phosphorylated at Y173.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Vav3 around the phosphorylation site of Y173.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000

Comment:

Isoform 1 and isoform 3 are widely expressed, both are expressed at very low levels in skeletal muscle. In keratinocytes, isoform 1 is less abundant than isoform 3. Isoform 3 is detected at very low levels, if any, in adrenal gland, bone marrow, spleen, fetal brain and spinal chord, in these tissues, isoform 1 is readily detectable.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for VAV3

Target: VAV3 (Vav 3 Oncogene (VAV3))

Alternative Name: Vav3 (VAV3 Products)

Molecular Weight: 100 kDa

Gene ID: 10451

UniProt: Q9UKW4

Pathways: Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway