DAPK3 antibody (AA 210-290)

Catalog No. ABIN6282188

Product Details anti-DAPK3 Antibody

Target: DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))

Binding Specificity: AA 210-290

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAPK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: DAPK3 is a protein encoded by the DAPK3 gene which is approximately 52,5 kDa. DAPK3 is localised to the nucleus and cytoplasm. It is involved in CDK-mediated phosphorylation and removal of Cdc6, dimerization of procaspase and pathways in cancer. It is a serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. It also plays a role in the regulation of smooth muscle contraction. DAPK3 is widely expressed in human tissues including the smooth muscle of the bladder. STJ92654 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of DAPK3 protein.

Specificity: DAPK3 Polyclonal Antibody detects endogenous levels of DAPK3 protein.

Characteristics: Rabbit polyclonal to DAPK3.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human DAPK3 around the non-phosphorylation site of T265.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000

Comment:

Widely expressed. Isoform 1 and isoform 2 are expressed in the bladder smooth muscle.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for DAPK3

Target: DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))

Alternative Name: DAPK3 (DAPK3 Products)

Synonyms: DAPK3 antibody, dapk3 antibody, wu:fc25b08 antibody, si:dkey-57k2.5 antibody, MGC114871 antibody, ZIP antibody, ZIPK antibody, dlk antibody, Dapkl antibody, death associated protein kinase 3 antibody, death-associated protein kinase 3 antibody, death-associated protein kinase 3 L homeolog antibody, DAPK3 antibody, dapk3 antibody, dapk3.L antibody, Dapk3 antibody

Molecular Weight: 52 kDa

Gene ID: 1613

UniProt: O43293