SEC16A antibody (Internal Region)

Catalog No. ABIN6285439

Product Details anti-SEC16A Antibody

Target: SEC16A (SEC16 Homolog A (SEC16A))

Binding Specificity: AA 980-1060, Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC16A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purpose: Sec16A is a protein encoded by the SEC16A gene which is approximately 233,5 kDa. Sec16A is localised to the endoplasmic reticulum membrane. It is involved in transport to the Golgi and subsequent modification and metabolism of proteins. It defines endoplasmic reticulum exit sites and is required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. It also mediates COPII vesicle formation at the transitional ER. Sec16A is ubiquitously expressed with higher expression in the pancreas. Mutations in the SEC16A gene may result in Charcot-Marie-Tooth disease. STJ95593 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Sec16A protein.

Specificity: Sec16A Polyclonal Antibody detects endogenous levels of Sec16A protein.

Characteristics: Rabbit polyclonal to Sec16A.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Sec16A

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:300
ELISA 1:20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for SEC16A

Target: SEC16A (SEC16 Homolog A (SEC16A))

Alternative Name: Sec16A (SEC16A Products)

Synonyms: KIAA0310 antibody, RP11-413M3.10 antibody, SEC16L antibody, p250 antibody, SEC16 homolog A, endoplasmic reticulum export factor antibody, SEC16A antibody

Molecular Weight: 233 kDa

Gene ID: 9919

UniProt: O15027