PDGFD antibody (C-Term)

Catalog No. ABIN6286221

Product Details anti-PDGFD Antibody

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Binding Specificity: AA 311-360, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal to PDGF-D.

Specificity: PDGF-D Polyclonal Antibody detects endogenous levels of PDGF-D protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human PDGF-D.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000

Comment:

Expressed at high levels in the heart, pancreas, adrenal gland and ovary and at low levels in placenta, liver, kidney, prostate, testis, small intestine, spleen and colon. In the kidney, expressed by the visceral epithelial cells of the glomeruli. A widespread expression is also seen in the medial smooth muscle cells of arteries and arterioles, as well as in smooth muscle cells of vasa rectae in the medullary area. Expressed in the adventitial connective tissue surrounding the suprarenal artery. In chronic obstructive nephropathy, a persistent expression is seen in glomerular visceral epithelial cells and vascular smooth muscle cells, as well as de novo expression by periglomerular interstitial cells and by some neointimal cells of atherosclerotic vessels. Expression in normal prostate is seen preferentially in the mesenchyme of the gland while expression is increased and more profuse in prostate carcinoma. Expressed in many ovarian, lung, renal and brain cancer-derived cell lines.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for PDGFD

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Alternative Name: PDGF-D (PDGFD Products)

Synonyms: IEGF antibody, SCDGF-B antibody, SCDGFB antibody, Scdgfb antibody, rSCDGF-B antibody, PDGFD antibody, 1110003I09Rik antibody, platelet derived growth factor D antibody, platelet-derived growth factor, D polypeptide antibody, PDGFD antibody, Pdgfd antibody

Molecular Weight: 42 kDa

Gene ID: 80310

UniProt: Q9GZP0

Pathways: RTK Signaling, Platelet-derived growth Factor Receptor Signaling