Myosin VI antibody (N-Term)

Catalog No. ABIN6287729

Product Details anti-Myosin VI Antibody

Target: Myosin VI (MYO6)

Binding Specificity: AA 40-120, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin VI antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Myosin VI is a protein encoded by the MYO6 gene which is approximately 149,6 kDa. Myosin VI is localised to the Golgi apparatus, nucleus and cytoplasm. It is involved in the PAK pathway, gap junction trafficking, actin nucleation and the RhoGDI pathway. It is a reverse-direction motor protein with ATPase activity that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. Myosin VI is expressed in most tissues including heart, brain, placenta, pancreas and spleen. Mutations in the MYO6 gene may result in deafness. STJ96437 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Myosin VI protein.

Specificity: Myosin VI Polyclonal Antibody detects endogenous levels of Myosin VI protein.

Characteristics: Rabbit polyclonal to Myosin VI.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Myosin VI

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for Myosin VI

Target: Myosin VI (MYO6)

Alternative Name: Myosin VI (MYO6 Products)

Synonyms: 95F antibody, 95F MHC antibody, CG5695 antibody, Dm 95F antibody, Dm95F antibody, Dmel\\CG5695 antibody, Dro95F antibody, JAG antibody, Jaguar antibody, Jar antibody, M6 antibody, MHC95F antibody, MYOVI antibody, Mhc95F antibody, MyoVI antibody, Myosin VI antibody, jag antibody, ms(3)06746 antibody, myosins VI antibody, DFNA22 antibody, DFNB37 antibody, BC029719 antibody, Tlc antibody, sv antibody, RGD1560646 antibody, CMY6 antibody, jaguar antibody, myosin VI antibody, jar antibody, LOC373230 antibody, MYO6 antibody, myo6 antibody, Myo6 antibody

Molecular Weight: 150 kDa

Gene ID: 4646

UniProt: Q9UM54

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization