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ADNP antibody (N-Term)

ADNP Reactivity: Human, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6287768
  • Target See all ADNP Antibodies
    ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))
    Binding Specificity
    • 15
    • 11
    • 9
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 80-160, N-Term
    Reactivity
    • 48
    • 35
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 56
    • 6
    • 1
    • 1
    Rabbit
    Clonality
    • 57
    • 6
    Polyclonal
    Conjugate
    • 31
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADNP antibody is un-conjugated
    Application
    • 50
    • 28
    • 13
    • 13
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    ADNP is a protein encoded by the ADNP gene which is approximately 123,5 kDa. It is a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. It may also increase the viability of certain cell types through modulation of p53 activity. ADNP is widely expressed with strong expression in heart, skeletal muscle, kidney and placenta. Mutations in the ADNP gene may result in Helsmoortel-van der Aa syndrome. STJ91502 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of ADNP protein.
    Specificity
    ADNP Polyclonal Antibody detects endogenous levels of ADNP protein.
    Characteristics
    Rabbit polyclonal to ADNP.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Synthesized peptide derived from human ADNP
    Isotype
    IgG
    Top Product
    Discover our top product ADNP Primary Antibody
  • Application Notes
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
    Comment

    Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • Target
    ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))
    Alternative Name
    ADNP (ADNP Products)
    Synonyms
    AA589558 antibody, mKIAA0784 antibody, ADNP1 antibody, activity-dependent neuroprotective protein antibody, activity dependent neuroprotector homeobox antibody, activity-dependent neuroprotector homeobox antibody, Adnp antibody, ADNP antibody
    Molecular Weight
    124 kDa
    Gene ID
    23394
    UniProt
    Q9H2P0
    Pathways
    Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process
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