ADNP antibody (N-Term)
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- Target See all ADNP Antibodies
- ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))
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Binding Specificity
- AA 80-160, N-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ADNP antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- ADNP is a protein encoded by the ADNP gene which is approximately 123,5 kDa. It is a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. It may also increase the viability of certain cell types through modulation of p53 activity. ADNP is widely expressed with strong expression in heart, skeletal muscle, kidney and placenta. Mutations in the ADNP gene may result in Helsmoortel-van der Aa syndrome. STJ91502 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of ADNP protein.
- Specificity
- ADNP Polyclonal Antibody detects endogenous levels of ADNP protein.
- Characteristics
- Rabbit polyclonal to ADNP.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human ADNP
- Isotype
- IgG
- Top Product
- Discover our top product ADNP Primary Antibody
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- Application Notes
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WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000 - Comment
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Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))
- Alternative Name
- ADNP (ADNP Products)
- Synonyms
- AA589558 antibody, mKIAA0784 antibody, ADNP1 antibody, activity-dependent neuroprotective protein antibody, activity dependent neuroprotector homeobox antibody, activity-dependent neuroprotector homeobox antibody, Adnp antibody, ADNP antibody
- Molecular Weight
- 124 kDa
- Gene ID
- 23394
- UniProt
- Q9H2P0
- Pathways
- Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process
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