Kyphoscoliosis Peptidase antibody

Catalog No. ABIN6288761

Product Details anti-Kyphoscoliosis Peptidase Antibody

Target: Kyphoscoliosis Peptidase (KY)

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Kyphoscoliosis Peptidase antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: CD1 is a protein encoded by the CD1A gene which is approximately 37 kDa. CD1 is localised to the cell membrane. It is involved in hematopoietic cell lineage, dendritic cells developmental lineage pathway and the innate immune system. This protein falls under the CD1 family of transmembrane glycoproteins which form heterodimers with beta-2-microglobulin. CD1 mediates the presentation of primarily lipid and glycolipid antigens to T-cells. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. CD1 is expressed in the blood, skin, heart and lymph nodes. Mutations in the CD1A gene may result in myofibroma. STJ96970 was developed from clone 9H6 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous CD1 proteins.

Specificity: The antibody detects endogenous CD1 proteins.

Characteristics: Mouse monoclonal to CD1.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Synthetic Peptide

Clone: 9H6

Isotype: IgG1

Application Details

Application Notes: IHC 1:200

Comment:

Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for Kyphoscoliosis Peptidase

Target: Kyphoscoliosis Peptidase (KY)

Alternative Name: CD1 (KY Products)

Synonyms: CD1 antibody, D9Mgc44e antibody, ky antibody, kyphoscoliosis peptidase antibody, Ky antibody, KY antibody

Gene ID: 909

UniProt: P06126

Pathways: Skeletal Muscle Fiber Development