TUBB2A antibody

Catalog No. ABIN6288905

Product Details anti-TUBB2A Antibody

Target: TUBB2A (Tubulin, beta 2A (TUBB2A))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBB2A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: β II tubulin is a protein encoded by the TUBB2A gene which is approximately 49,9 kDa. β II tubulin is localised to the cytoplasm and cytoskeleton. It is involved in Sertoli-Sertoli cell junction dynamics, development Slit-Robo signalling and the GPCR pathway. Tubulin is the major constituent of microtubules. Microtubules are key participants in processes such as mitosis and intracellular transport and are composed of heterodimers of alpha- and beta-tubulins. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. β II tubulin is expressed in the nervous system, eye, skin and lung. Mutations in the TUBB2A gene may result in lung mucoepidermoid carcinoma. STJ97053 was developed from clone Mix and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous β II tubulin protein.

Specificity: The antibody detects endogenous β II tubulin protein.

Characteristics: Mouse monoclonal to β II tubulin.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Synthetic Peptide

Clone: Mix

Isotype: IgG1

Application Details

Application Notes: WB 1:50000-100000
IP 1:200

Comment:

High expression in brain, where it represents 30% of all beta-tubulins.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for TUBB2A

Target: TUBB2A (Tubulin, beta 2A (TUBB2A))

Alternative Name: beta II tubulin (TUBB2A Products)

Synonyms: TUBB antibody, TUBB2 antibody, dJ40E16.7 antibody, M(beta)2 antibody, Tubb2 antibody, TUBB2A antibody, tubb2a antibody, zgc:112335 antibody, tubulin beta 2A class IIa antibody, tubulin, beta 2A class IIA antibody, tubulin beta-2A chain antibody, tubulin, beta 2A class IIa antibody, TUBB2A antibody, Tubb2a antibody, LOC478701 antibody, LOC100079040 antibody, LOC100349792 antibody, LOC100599614 antibody, tubb2 antibody

Gene ID: 7280

UniProt: Q13885

Pathways: Microtubule Dynamics, M Phase