Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

GDF5 antibody

GDF5 Reactivity: Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6290098
  • Target See all GDF5 Antibodies
    GDF5 (Growth Differentiation Factor 5 (GDF5))
    Reactivity
    • 69
    • 33
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 73
    • 3
    • 3
    • 3
    • 1
    Rabbit
    Clonality
    • 77
    • 6
    Polyclonal
    Conjugate
    • 36
    • 13
    • 9
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GDF5 antibody is un-conjugated
    Application
    • 69
    • 40
    • 40
    • 9
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide of human GDF5
    Isotype
    IgG
    Top Product
    Discover our top product GDF5 Primary Antibody
  • Application Notes
    WB 1:500 - 1:2000
    Comment

    Predominantly expressed in long bones during embryonic development, Expressed in monocytes (at protein level)

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    GDF5 (Growth Differentiation Factor 5 (GDF5))
    Alternative Name
    GDF5 (GDF5 Products)
    Synonyms
    CDMP1 antibody, gdf antibody, gdf-5 antibody, GDF5 antibody, BDA1C antibody, BMP14 antibody, LAP4 antibody, OS5 antibody, SYM1B antibody, SYNS2 antibody, Cdmp-1 antibody, bp antibody, brp antibody, Cdmp1 antibody, growth differentiation factor 5 L homeolog antibody, growth differentiation factor 5 antibody, gdf5.L antibody, GDF5 antibody, Gdf5 antibody
    Background
    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis.
    Molecular Weight
    55.411 kDa
    Gene ID
    8200
    UniProt
    P43026
You are here:
Support