CLCN4 antibody

Catalog No. ABIN6290202

Product Details anti-CLCN4 Antibody

Target: CLCN4 (Chloride Channel 4 (CLCN4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCN4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human CLCN4

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Abundant in skeletal muscle and also detectable in brain and heart

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for CLCN4

Target: CLCN4 (Chloride Channel 4 (CLCN4))

Alternative Name: CLCN4 (CLCN4 Products)

Synonyms: Clc4-2 antibody, Clcn4 antibody, CLC4 antibody, ClC-4 antibody, ClC-4A antibody, Clcn4-2 antibody, chloride voltage-gated channel 4 antibody, chloride channel, voltage-sensitive 4 antibody, CLCN4 antibody, clcn4 antibody, Clcn4 antibody

Background: The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins.

Molecular Weight: 84.917 kDa

Gene ID: 1183

UniProt: P51793