CLDN8 antibody

Catalog No. ABIN6290246

Product Details anti-CLDN8 Antibody

Target: CLDN8 (Claudin 8 (CLDN8))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLDN8 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human CLDN8

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Expressed in the epididymis, mainly in the caput segment

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for CLDN8

Target: CLDN8 (Claudin 8 (CLDN8))

Alternative Name: CLDN8 (CLDN8 Products)

Synonyms: zgc:91900 antibody, wu:fa01e05 antibody, CLDN8 antibody, AI648025 antibody, claudin 8 antibody, CLDN8 antibody, cldn8 antibody, Cldn8 antibody

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.

Molecular Weight: 24.845 kDa

Gene ID: 9073

UniProt: P56748

Pathways: Hepatitis C